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Two genomic researchers working in a lab

Genomics Group

The Genomics Group at Nova Southeastern University's Institute for Neuro-Immune Medicine is dedicated to unraveling the complex causes and developing more accurate diagnostics for a range of multi-symptom disorders, including Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Gulf War Illness (GWI).

Our research leverages cutting-edge sequencing technologies, such as bulk and single-cell RNA sequencing, genome sequencing, and DNA methylation studies using Whole Genome Bisulfite Sequencing (WGBS) and Reduced Representation Bisulfite Sequencing (RRBS). Additionally, we employ NanoString nCounter technology to provide valuable insights into gene expression patterns.

By collaborating closely with clinical and computational biology experts at INIM, we combine clinical, laboratory, and computational methods to analyze and validate our findings. Our research aims to shed light on the underlying biological mechanisms of these debilitating conditions and ultimately improve patient outcomes.

Our Team

Dr Lubov Nathanson headshotAssociate Professor, Director, Genomics Group, Institute for Neuro Immune Medicine, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University

Lubov Nathanson, Ph.D. is an associate professor at Nova Southeastern University, where her research efforts focus on translational genomics. Her combined expertise in bioinformatics, molecular biology, biochemistry, and systems biology allows her to evaluate complex disease states that impact multiple organ systems and have complicated mechanisms of disease onset, activity, and progression. Her current research efforts focus on gaining insight into the epigenomic and transcriptional changes involved in multi-symptom disorders including Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Gulf War illness (GWI). Specifically, her ongoing research involves identifying biomarkers and mechanisms of ME/CFS and GWI using approaches such as bulk and single-cell RNA sequencing, micro RNA expression and DNA methylation to identify transcriptional regulators that result in characteristic symptomatology associated with ME/CFS and GWI.

View Full Biography and List of Publications

Dr. Rajendra Pangeni in the labAssistant Professor of Genomics, Institute for Neuro-Immune Medicine, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University

Rajendra Pangeni, Ph.D., completed his Ph.D. in molecular oncology from the University of Wolverhampton, UK. During his Ph.D., he worked on DNA methylation dysregulation in breast cancer metastases to the brain using genome wide and laboratory approaches. He received his post-doctoral trainings from Northwestern University Chicago and City of Hope National Medical Center, Duarte, California. During his post doctoral works, Dr. Pangeni worked on glioblastoma (one of the most aggressive brain tumors) and non-small cell lung cancer using genome wide DNA methylation array, RNA sequencing, stem cells, mouse models, and other genetic and epigenetics approaches.

View Full Biography and List of Publications

Get in Touch

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