Barry and Judy Silverman College of Pharmacy—Ph.D. Program 215 drugs; use, abuse, and misuse as medical, psychological, and social concepts; drug importation, manufacture, and distribution (including both the legal and illegal drug industries); perspectives on the etiology of drug use/abuse; drug abuse prevention and educational programs; and approaches to drug abuse treatment. (48-0-3) PHRE 5216/7216—Pharmaceutical Polymers This course presents basic concepts and properties of polymers as related to formulation, development, and design of pharmaceutical dosage forms and products. It describes how basic principles of polymers—structural, physical, chemical, and mechanical properties—can be utilized in modifying and developing current and novel pharmaceutical products. Moreover, the course highlights important areas of polymer applications in controlled drug delivery, targeted drug delivery, tissue engineering, nanotechnology, and medical devices. (48-0-3) PHRE 5224/7223—Drugs of Abuse This course covers types of substances abused, methods and routes of administration, the pertinent toxicokinetics, the pharmacological/ toxicological mechanisms, and the clinical manifestations of drug abuse. The anatomical and neurochemical substrates of drugs of abuse are also described. Treatment of intoxication and withdrawal, societal impact of drug abuse, legal implications, and current trends of substance abuse are addressed as well. (48-0-3) PHRE 5244/7252—Fundamentals of Pharmacognosy This course exposes graduate students to the field of pharmacognosy, with an emphasis on medicinal products derived from plants and other natural sources. The major classes of medicinally active natural products, their origin (nomenclature + taxonomy), structure, biosynthesis, and mode of action will be covered. The naturally derived constituents and their therapeutic efficacy will be discussed. Students will be required to develop a monograph for a bioactive plant or marine species, including a comprehensive summary of the peer-reviewed research available regarding its pharmacological profile. (48-0-3) PHRE 5351/7350—Contemporary Issues in Pharmacy This course is designed to explore a broad spectrum of contemporary issues related to pharmacy practice, pharmaceutical industry, third-party payment, and health policy. It aims to increase student awareness and understanding of the change in pharmacy practices and their impacts to the U.S. healthcare system. (48-0-3) PHRE 5432/7431—Oncologic Treatments and Pharmacogenomics This course introduces the basic molecular concepts of cancer and pharmacogenomics in the context of cancer treatment. It presents the current methodologies used in cutting-edge oncology for the treatment of two of the most common types of cancer: breast and colon. The standard-of-care combinatorial regimens will be presented, as well as the treatment scenarios that are applied to advanced-stage and recurrent disease. Drugs that have increased patient tolerance to these genotoxic regimens will also be discussed. Finally, the application of next-generation sequencing of tumor DNA or RNA to determine which of the more than 300 druggable mutations exist in these tumors will be discussed, primarily in the cancer-recurrence setting. Prognostic tests based on RNA expression from tumors will be covered. Discussion of the rationale for insurance coverage of pharmacogenomic variability will be covered as well. The impact of oncologic pharmacogenomics on future clinical trials will also be examined. (48-0-3) PHRE 5516/7515—Health Disparities and Chronic Diseases: The Role of the Pharmacist This course presents the main causes and pathways to health disparities in the United States. It focuses on chronic diseases, such as diabetes, cancer, and cardiovascular diseases. Emphasis is given to disparities associated with access to medication and pharmacy services and to adherence. Students learn about pharmacy-led interventions aimed at reducing health disparities. They are expected to use epidemiological data to study the disparities and to formulate recommendations to the pharmacy field. Students are assessed through hands-on, structured assignments. (48-0-3) PHRE 5999—Research in the Pharmaceutical Sciences In this course, students work under the direction/supervision of one or more faculty members in a research laboratory. Students are involved in planning and executing an approved research project using basic techniques of scientific research. Students will be awarded 3 or 4 credits on the basis of 48 laboratory hours per credit. (0-[144–192]-[3–4]) PHRE 7071—Essentials of Project Management for Pharmacy I This course serves as an introduction to project management terminology, knowledge, concepts, and skills used in the current work environment. It lays the foundation of project management methods and best practices. Topics covered guide the student on the use of project management tools and techniques to successfully initiate, plan, execute, monitor, and close a project. Students learn about planning, scheduling, organizing, and implementing projects and explore current practices in project management from a pharmacy perspective. (48-0-3) PHRE 7081—Essentials of Project Management for Pharmacy II This course will prepare students for the project management work environment through a deeper understanding of leadership and team dynamics. In addition, the course introduces negotiation techniques, ethical principles and practices, and professional standards in the workplace. Topics covered guide the student on Lean Six Sigma (LSS) tools and techniques to achieve operational excellence and improve
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