Barry and Judy Silverman College of Pharmacy—Pharm.D. Program 189 multifunctional drug delivery systems (DDSs) and drug delivery devices (DDDs) using various advanced nanobiomaterials. The course elaborates on the applications of nanoscale multimodal DDSs/DDDs in targeted therapy of detrimental diseases, such as solid tumors. It outlines cell-/tissue-specific targeted therapy and provides overviews on the applications of theranostics for simultaneous diagnosis and therapy. (32-0-2) PHRE 5431—Oncologic Treatments and Pharmacogenomics This course introduces the basic molecular concepts of cancer and pharmacogenomics in the context of cancer treatment. It presents the current methodologies used in cutting-edge oncology for the treatment of two of the most common types of cancer: breast and colon. The standard-of-care combinatorial regimens will be presented, as well as the treatment scenarios that are applied to advanced-stage and recurrent disease. Drugs that have increased patient tolerance to these genotoxic regimens will also be discussed. Finally, the application of nextgeneration sequencing of tumor DNA or RNA to determine which of the more than 300 druggable mutations exist in these tumors will be discussed, primarily in the cancer-recurrence setting. Prognostic tests based on RNA expression from tumors will be covered. Discussion of the rationale for insurance coverage of pharmacogenomics will be covered as well. The impact of oncologic pharmacogenomics on future clinical trials will also be examined. (32-0-2) PHRE 5447—Regulatory Affairs This course provides exposure to the important and critical area of drug regulatory matters. It describes the role of federal laws, regulations, and the structure and operation of the U.S. Food and Drug Administration. It also compares similar agencies in other countries. (32-0-2) PHRE 5505—Consulting Pharmacy in Long-Term Care This course focuses on the practice of consulting pharmacy practice in long-term care facilities. It provides an overview of geriatric consulting statutes that regulate the activity of the consultant pharmacist, the Healthcare Financing Administration survey guidelines, and the types of facilities required to have a consultant pharmacist. Students will apply the Pharmacists’ Patient Care Process in addressing geriatric patient medication-related needs in this setting. Prerequisite: P3 Standing/PHRC 5935 (32-0-2) PHRE 5513—Special Population Needs and the Role of the Pharmacist This course uses the framework of social determinants of health and the ecological model and provides a holistic perspective to vulnerable and special populations. Students have an opportunity to explore the needs of special populations from a pharmacist’s perspective, enabling students to self-assess their preconceived knowledge and gain a new perspective to practice pharmacy. Students acquire knowledge about factors that influence and intersect with vulnerable populations. Students are expected to design an intervention for a population of their interests, applying the knowledge and skills they have acquired. This is an online course that requires students to work independently and with other class members to complete a project. (32-0-2) PHRE 5515—Health Disparities and Chronic Diseases: The Role of the Pharmacist This course presents the main causes and pathways to health disparities in the United States. It focuses on chronic diseases, such as diabetes, cancer, and cardiovascular diseases. Emphasis is given to disparities associated with access to medication, access to pharmacy services, and to adherence. Students learn about pharmacy-led interventions aimed at reducing health disparities. They are expected to use epidemiological data to study the disparities and to formulate recommendations to the pharmacy field. Students are assessed through hands-on, structured assignments. (32-0-2) PHRE 5517—Biologics and Beyond This course introduces and familiarizes students with biologic drugs, FDA-approved biosimilars, antibody-drug conjugates, gene medicine products, and cell therapy products. Mechanisms of actions, disposition principles, dosing and product handling aspects, therapeutic use, drawbacks, and ongoing trials/research are discussed. Students will work in teams to study the characteristics of biologics by disease categories and drug types. (32-0-2) PHRE 5551—Nutrition and Wellness in Pharmacy Practice This course provides strategies to improve nutritional status, health, and wellness. It highlights nutritional wellness, foods, and diets that may be used to help maintain or improve health. It reviews epidemiological and genetic aspects of individuals, nutritional deficiencies, and environmental causes of illness and disease. Additionally, it presents the tools needed to conduct nutritional and environmental assessments, comprehend patients’ anthropometrics, and provide nutritional guidance and wellness plans for patients. (32-0-2) PHRE 5619—Pharm.D./D.M.D. Interprofessional Experience This interprofessional education (IPE) course provides an opportunity to engage in multidisciplinary healthcare. Pharmacy and dental students will work together at a dental clinic exclusively serving patients with HIV. In collaboration with dental students, pharmacy students will obtain accurate medication histories from patients, update medical records appropriately, and provide patient education on antiretroviral therapy and dental hygiene. Didactic lectures will address overall health management of individuals with HIV. Students are expected to be at the dental clinic approximately five hours per week for seven weeks. Prerequisite: PHRC 5935 (16-48-2)
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